The first controlled study examining marijuana as a treatment for post-traumatic stress disorder needs just a handful more U.S. military veterans to volunteer as test subjects before it can be completed, the study’s nonprofit sponsor announced Thursday.
More than 2.7 million men and women have been deployed to combat zones in Iraq and Afghanistan since 2001. As many as 20 percent of veterans may return with Post-Traumatic Stress Disorder (PTSD), according to Department of Veterans Affairs (VA) data.
Many combat vets anecdotally report using cannabis to successfully treat symptoms of PTSD, but without data from a controlled study, mainstream medicine—and the VA health system—have been slow to accept marijuana as a treatment, despite pressure from Trump Administration officials who suggest cannabis may be effective.
After some difficulty, a study in Arizona sponsored by the Multidisciplinary Association for Psychedelic Studies (MAPS) examining smoked marijuana as a treatment is near full enrollment and is expected to finish on time, the organization announced.
The study can accept seven more volunteer test subjects, said lead researcher Dr. Sue Sisley, a physician and psychiatrist who has been working on the study for a decade.
“We only have seven spots available for #veterans to still be enrolled in the study, but they must be screened before the end of October in order to be eligible.” —@SueSisleyMDhttps://t.co/2Mqt7HcFHi #PTSD #Medicine #Marijuana #PressRelease
— MAPS (@MAPS) August 9, 2018
Participants “must be adult military veterans with chronic, treatment-resistant PTSD,” according to Sisley. Research will be conducted in Phoenix, Arizona, where veterans will make 17 outpatient study visits over the course of 12 weeks.
The study is progressing despite significant challenges, including a lack of financial assistance from the VA, which has also blocked Sisley from entering its hospitals in search of test subjects.
Sisley was summarily discharged from her position as a professor at the University of Arizona in the study’s early stages, a firing that some say was politically motivated.
After losing the imprimatur of the University of Arizona in 2013, another research university that initially planned to sponsor with Sisley, Johns Hopkins University in Baltimore, also abruptly cut ties with Sisley and the study.
Hopkins announced its departure after Sisley publicly criticized the quality and potency of the research-grade marijuana provided by the federal government.
The National Institute on Drug Abuse still has a monopoly on the marijuana available to researchers in the United States, which is grown on a farm operated by the University of Mississippi. The cannabis is low-quality and low-potency, critics say, and bears little resemblance to the marijuana found at dispensaries and on the black market.
In the waning months of the Obama administration, the Drug Enforcement Administration announced plans to license additional growers of cannabis for research, but the Trump administration has not acted on the more than two dozen applications it has received to date, something that has angered members of Congress from both parties.
In addition to MAPS, Sisley’s study is funded by a $2.156 million grant from the Colorado Department of Public Health.
According to researchers, the study “will provide physicians, patients, scientists, and regulators with critical knowledge regarding whether marijuana benefits individuals with PTSD, whether adverse consequences occur, and the impact of the chemical composition of marijuana, specifically ∆-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), on clinical outcomes. The data from the trial will be finalized in early 2019, after which the results will be prepared for publication.”
The study is still the only of its kind, despite a recent admission from the VA that it could study cannabis.
Scientists Actually Did A Study To Confirm That Marijuana Causes The Munchies
Science has confirmed that marijuana really does cause the munchies.
More precisely, a new study found that sales of commonly munched on products like ice cream, cookies and chips tend to go up after states legalize cannabis.
To do so, a team of researchers developed complicated mathematical formulas like the one featured below and analyzed a trove of retail scanner data.
The study indicates that the “widespread urban myth” that cannabis stimulates hunger and drives people to gorge on goodies is a myth no longer. The researchers looked at retail scanner data in more than 2,000 counties across the U.S. from 2006 to 2016 to determine whether states that legalize marijuana for adult use experience increases in the sale of high-calorie food items.
Past studies on the munchies have relied on data that’s “correlational and indirect,” they wrote. This paper, meanwhile, tested the hypothesis by factoring in the “differences in timing of the legalization of recreational marijuana across states” and specifically comparing “retail food purchases for the subsample of contiguous counties across [recreational marijuana law] and non-[recreational marijuana law] shared borders only.”
The study found causal evidence that legalizing cannabis was associated with higher so-called “junk food purchases.
Shortly after a state’s legal marijuana system became effective, average monthly sales of ice cream, cookies and chips jumped 3.1 percent, 4.1 percent and 5.3 percent, respectively. And that was the case even after the researchers accounted for “state- and pair-specific time trends.”
“The increase in sales starts at the time of the legislation becomes effective,” the study authors wrote. “The effect slightly decreases in the semesters thereafter for ice cream and chips, but not for cookies.”
That’s probably a welcome finding for Girl Scouts in Colorado. The state’s chapter recently lifted a ban on selling cookies outside of “adult-oriented businesses” such as marijuana stores, where the scouts can rest assured they’ll find a hungry customer base.
Study Shows That Bees Like Hemp, And That’s Great News For The Environment
Farmers (and Sen. Mitch McConnell) aren’t the only ones who are excited about hemp. According to a recent study, the crop also attracts a variety of bees—and that can help inform ecologically sustainable agriculture practices.
For the study, published this month in the journal Biomass and Bioenergy, researchers at Colorado State University set up 10 traps at industrial hemp fields in northern Colorado and collected bees over the course of five days during peak flowering season.
There are few other crops that pollinate in the region during the same timeframe, so the team wanted to know whether the non-psychoactive cannabis cousin of marijuana represented “a potentially valuable source of pollen for foraging bees,” which play a critical role in maintaining “sustainable productivity in natural and agricultural ecosystems.”
When the researchers looked at their collection, they found almost 2,000 bees from 23 different bee genera. Most of those (38 percent) were classic honeybees, but there were also specialized genera such as Melissodes bimaculata and Peponapis pruinosa that turned up in surprisingly “high proportions.”
The sample also indicated that hemp flowers are uniquely attractive to bees because previous reports looking at bee abundance and diversity for crops like genetically modified canola flowers didn’t produce the same volume or variety.
“Industrial hemp can play an important role in providing sustained nutritional options for bees during the cropping season.”
The study could prove helpful as ecologists attempt to address declining bee populations. The insects “continue to face debilitating challenges due to a number of different stressors,” the researchers wrote, but chief among them is the overall health of their respective habitats.
Finding a suitable pollinating crop to improve their habitats is, therefore, critical to the lives of bees and the ecosystems they occupy. Hemp “can thus be an ecologically valuable crop whose flowers are attractive to managed honey bees and a wide range of wild bees,” the researchers concluded.
“In addition, access to crucial phytochemicals through pollen and nectar from diverse plant sources is important for improved survival and pathogen tolerance in honey bees,” the team wrote. “Further studies analyzing the nutritive value of hemp pollen, would provide strong evidence in support of the ecological benefits.”
But the study also includes a warning: as hemp cultivation expands, which experts expect it will significantly since it has recently been federally legalized, there will be an increased risk of insect pests infecting the crop. And so the researchers said they “strongly urge that the information generated in this study on the diversity and abundance of bees on hemp be used to develop an integrated pest management plan designed to protect pollinators while controlling pests.”
Photo courtesy of Pixabay.
States With Legal Medical Marijuana Have Lower Teen Use Rates, Large-Scale Study Finds
Contrary to often-expressed fears of marijuana legalization opponents, teens living in states that allow medical cannabis are actually less likely to use the drug compared to those in non-legal states.
That’s the result of a new study published in The American Journal of Drug and Alcohol Abuse.
Researchers at Boston College looked at national youth drug surveys from 1999 to 2015—a data set that involved more than 860,000 adolescents across the United States. They investigated how self-reported marijuana use changed in states that have either decriminalized cannabis possession or legalized it for medical purposes.
And while opponents of legalization have long argued that loosening marijuana laws would drive more youth to consume cannabis, the study showed the opposite. The enactment of medical cannabis laws was associated with 1.1 percentage point reduction in marijuana use among teens.
“We found that for every group of 100 adolescents, one fewer will be a current user of marijuana following the enactment of medical marijuana laws,” study author Rebekah Levine Coley said in a press release.
That decline was even more pronounced within certain subgroups. For example, 3.9 percent fewer black adolescents and 2.7 percent fewer Hispanic adolescents used marijuana in legal medical cannabis states.
The trend also held true after researchers accounted for factors such as state demographics and economic trends. What’s more, the reductions in youth marijuana use were more significant the longer a state had a medical cannabis system in effect.
“Some people have argued that decriminalizing or legalizing medical marijuana could increase cannabis use amongst young people, either by making it easier for them to access, or by making it seem less harmful,” Coley said. “However, we saw the opposite effect.”
“We were not able to determine why this is, but other research has suggested that after the enactment of medical marijuana laws, youths’ perceptions of the potential harm of marijuana use actually increased. Alternatively, another theory is that as marijuana laws are becoming more lenient, parents may be increasing their supervision of their children, or changing how they talk to them about drug use.”
States that have simply decriminalized cannabis possession did not experience the same reductions in youth marijuana use, the study also found. There were slight declines in usage among 14-year-olds and Hispanic youth, but the broader reductions were only seen in medical marijuana states.
Photo courtesy of Nicholas C. Morton.