Legalizing marijuana for medical or recreational purposes isn’t associated with an uptick in traffic fatalities, according to a new study released this month.
Kansas State University graduate student Andrew Young looked at data on average traffic fatalities over 23 years and used two models to assess the impact of cannabis reform on road safety.
“[L]egalizing marijuana is not found to be a statistically significant predictor of fatality rates,” he concluded. “This finding means that the legalization of marijuana for both medical and recreational purposes is not associated with either a reduction or increase in fatalities per 100,000 vehicle miles traveled.”
After conducting a regression analysis that turned up no evidence that state legalization efforts result in an increase or decrease in traffic fatalities, Young used a difference-in-difference model to compare the traffic fatality rates in legal cannabis states and control states. The more tailored analysis covered an eight-year timeline, starting five years before the state in question legalized marijuana.
No concrete trends emerged from that analysis.
In Arizona, where medical cannabis is legal, average traffic fatalities mirrored those of Wyoming and South Dakota, where marijuana is prohibited.
The fatal car accident rate was considerably higher in Colorado compared to Georgia and Iowa in 2001, but that trend started happening prior to medical cannabis legalization and also leveled out by 2003.
Traffic fatalities dropped in Washington D.C. following the City Council’s 2010 approval of medical cannabis, and were lower than in Utah or Virginia, which prohibit marijuana.
“The results of the analysis suggest that there is no statistically [significant] relationship between marijuana legalization and fatal crashes,” Young wrote. “These findings suggest that concerns of policy makers and the public that legalizing marijuana will worsen road safety are not entirely founded.”
“According to the difference-in-differences model, the recent upward trend of traffic fatality rates nationwide is not a result of medical marijuana legalization. In fact, the legalization of marijuana is not found to be a predictor of traffic fatalities,” he wrote.
The main limitation of the study, which has not been published in a peer-reviewed journal, concerns states where cannabis has been legalized for adult use. The small sample size, at least compared to medical marijuana states, means the analysis might not have been able to “fully estimate the impact of recreational cannabis on traffic safety.”
That said, the findings reflect those of several past studies that have also failed to identify a statistically significant relationship between legalization and road safety.
Another recent study also debunked the myth that traffic accidents spike on the cannabis holiday 4/20.
Top Federal Drug Official Says There’s ‘No Evidence’ That Occasional Marijuana Use Is Harmful For Adults
The head of the nation’s top federal drug research agency says that she’s yet to see evidence that occasional marijuana use by adults is harmful.
National Institute on Drug Abuse (NIDA) Director Nora Volkow made the remarks in an interview with FiveThirtyEight that was published on Tuesday. It’s a notable admission given that the agency has historically gone to great lengths to highlight the potential risks of cannabis consumption.
“There’s no evidence to my knowledge that occasional [adult] marijuana use has harmful effects. I don’t know of any scientific evidence of that,” Volkow said. “I don’t think it has been evaluated. We need to test it.”
The quote stood out in an article that generally attempts to highlight possible risks of cannabis use while providing an overview of studies that run the gamut on marijuana health impacts. Volkow also said she found it “surprising” that research has indicated that cannabis consumers tend to have a lower body mass index (BMI).
“BMI is lower in marijuana users, and that was very surprising, and yet we know that high BMI, particularly the older you get, can have negative effects,” she said. “This is why we need to study it.”
This is certainly not to say that the NIDA director supports marijuana commercialization efforts. But to advocates, it’s encouraging to see a federal health official rely on the science and acknowledge that, as it stands, the evidence hasn’t pointed to serious harms for adults who occasionally use cannabis.
She did tell FiveThirtyEight that she is “absolutely” concerned about use by young people and said that daily consumption of high-THC products ““can have harmful effects even on the adult brain.”
But Volkow has taken a fairly level-headed approach to marijuana, pointing out potential dangers for adolescents and pregnant women, for example, while at the same time acknowledging that her expectations about the impact of state-level reforms haven’t always come to fruition.
For example, she recognized in a podcast interview released in August that cannabis legalization has not led to increased youth use despite her prior fears, and she spoke about the therapeutic potential of certain psychedelics that have long been deemed “dangerous” under federal law.
The official has also emphasized the need to address substance misuse with a public health lens, rather than subject people to criminalization for using drugs.
She said in an op-ed earlier this month that “stigma remains one of the biggest obstacles to confronting America’s current drug crisis,” and the government bears some responsibility in perpetuating those stigmas.
“Government policies, including criminal justice measures, often reflect—and contribute to—stigma,” she said. “When we penalize people who use drugs because of an addiction, we suggest that their use is a character flaw rather than a medical condition. And when we incarcerate addicted individuals, we decrease their access to treatment and exacerbate the personal and societal consequences of their substance use.”
Volkow also talked about how decriminalization, coupled with increased treatment, would represent a superior alternative to incarcerating people over drugs in a recent interview with Marijuana Moment.
In other recent remarks, she argued that there’s no need for further research to prove that the criminalization of drugs has disproportionately impacted communities of color.
And when it comes to marijuana research, the official has said that scientists should be allowed to investigate products from state-legal dispensaries instead of using only government-grown plants.
NIDA separately submitted a report to congressional lawmakers emphasizing that the Schedule I status of controlled substances like cannabis is preventing or discouraging research into their potential risks and benefits.
It also said that current restrictions that block scientists from studying the actual cannabinoid products that consumers can purchase at dispensaries is impeding research to an extent that constitutes a public health concern.
Photo courtesy of Martin Alonso.
Dogs Are Being Exposed To Marijuana Through Human Poop And Pet Owners Should Beware, Study Finds
A word of caution to dog owners: apparently some canines are getting intoxicated off marijuana by eating the feces of people who’ve consumed cannabis, according to a new study.
Dogs are natural scavengers, and so the instinct to eat poop—while gross—is just a fact of life. But a team of Australian researchers found that, in some cases, that instinct can become dangerous, warranting the attention of puppy parents.
The study, published in the Australian Veterinary Journal, looked at 15 cases of confirmed THC toxicosis in dogs who were suspected of, or observed to have, ingested human feces in Melbourne from 2011-2020.
The dogs presented symptoms of incoordination, dilated pupils, urinary incontinence and stupor. Urine tests from eight of the dogs showed THC metabolites in their system.
However, study author Clara Lauinger told Marijuana Moment that this shouldn’t necessarily be taken to mean that any level of THC is toxic in dogs.
“The animals in my study had ingested an unknown quantity of feces that contained an unknown concentration of THC and so one would assume this concentration would be at a level that clearly caused toxicity,” she wrote in an email. “However this does not mean that all THC ingestions can lead to toxicity.”
In fact, there are other studies where animals were administered a controlled dosage of THC and “not a single one of them displayed any adverse effects that we might see with toxicity,” she said.
“There are so so many anecdotal reports of the huge benefits that THC administration has on animals, albeit reports are from owners perception rather than peer reviewed research, but this does not mean the industry should disparage THC as a therapeutic agent,” Lauinger said.
Most of the dogs in her new study apparently ate the poop at local parks, while others ingested it at the beach, camp sites and walking trails.
“All dogs survived to discharge. Ingestion of human feces containing THC may lead to marijuana toxicosis in dogs,” the study states. “Veterinary staff and owners should be attentive in regard to using appropriate hygiene measures when managing these dogs.”
The authors said that there are a number of reasons that a dog might eat poop—or, put scientifically, engage in coprophagy. But they floated one possibility for the marijuana-specific feces-eating trend: “It is possible that the presence of marijuana in feces increases its attractiveness for ingestion by altering its scent, texture and/or taste.”
Also, while this study is limited to data on about two dozen dogs in one city of Australia, the authors also said that the habit “might be more common than what owners report,” pointing to Google search results from people reporting a dog ate feces and exhibited signs of lethargy.
The idea of dogs getting high off THC-containing human waste might seem like a stretch on its own, but the study also explains that canines have more cannabinoid receptors than humans, “making dogs more sensitive to the effects of THC.”
“In conclusion, this case series suggests that ingestion of feces produced by a human marijuana user may lead to signs of marijuana toxicosis,” the researchers said. “Clinical signs of toxicosis were similar to those previously reported for dogs with conrmed marijuana toxicosis though gastrointestinal signs were not the most common feature despite coprophagy.”
“Veterinary staff and owners should be mindful of this exposure source to ensure appropriate hygiene measures are taken when managing these dogs,” the study says.
Lauinger said that there “needs to be an industrywide understanding of the fact that there are so many different strains of cannabis and each of these strains has different cannabinoid profiles that have possible potential for beneficial therapeutic effects.”
“These strains could be researched with a focus on what ones are suitable for animals and at what dose rather than blanketing all strains as being toxic,” she said. “I hope the public can be patient and also get behind us researching the dosing more.”
While there are clear concerns about dogs ingesting excess levels of THC, studies have found promising results when it comes to the therapeutic potential of other cannabinoids like CBD for pets.
For example, dogs with epilepsy experience considerably fewer seizures when treated with CBD oil, a study published in the journal Pet Behaviour Science in 2019 found.
The prior year, a separate study determined that CBD can alleviate the symptoms of osteoarthritis in dogs.
The Food and Drug Administration (FDA), for its part, has repeatedly warned pet owners about using CBD to treat firework-related anxiety in pets around the July 4 holiday.
“You should be aware that FDA has NOT evaluated these products and can’t say whether they are safe or effective, how they are manufactured, or whether they contain CBD,” the agency said this year.
Photo courtesy of Pexels.
Psychedelics Use Associated With 55 Percent Decrease In Daily Opioid Consumption, Study Finds
The use of psychedelics like LSD, psilocybin, mescaline and DMT is associated with a significant decrease in illicit opioid consumption, according to a new study.
Researchers looked at data from “three harmonized prospective cohorts of community-recruited” people with substance misuse disorders. A total of 3,813 individuals were involved, including 1,093 who reported illicit opioid consumption and 229 who said they’d used psychedelics in the past six months.
“Recent psychedelic use was associated with 55% reduced odds of daily opioid use,” the Vancouver-based study, published last week in the Journal of International Drug Policy, found.
While there have been numerous studies connecting legal marijuana access to reduced opioid use and fewer overdose deaths, this is “the first longitudinal study to link psychedelic use with lower daily opioid use,” the paper says.
“Over study follow-up after adjusting for a range of potential confounders, psychedelic use remained independently associated with a significantly reduced odds of subsequent daily opioid use,” the study states. “While confirmation in other settings is required, these findings align with growing evidence that psychedelic use may be associated with detectable reductions in subsequent substance use including illicit opioid use.”
While there’s not a clear explanation for the trend—and the researchers urged additional studies—psychedelics like psilocybin and MDMA have been touted as potentially powerful tools in mental health treatment, effectively treating conditions like severe depression, post-traumatic stress disorder and addiction.
“These findings align with growing evidence demonstrating that psychedelic use may be associated with detectable reductions in subsequent opioid use, and warrant further research on psychedelics for opioid and other substance use disorders,” the study’s lead author, Elena Argento of the University of British Columbia, told Marijuana Moment.
“This study found naturalistic psychedelic use to be independently associated with a significantly reduced odds of subsequent daily illicit opioid use among a community-based sample of [people who use drugs],” the study concluded. “More research with controlled trials and longer-term follow-up is required to elucidate the therapeutic potential of psychedelics to augment existing interventions for substance use disorders, including among more diverse populations. Additional qualitative studies would also provide opportunities to improve understanding of the possible psycho-social mechanisms underpinning psychedelic experiences.”
Another recent study found that when people use cannabis together with psychedelics, it was “associated with higher scores of mystical-type experience, ego-dissolution and visual alterations.”
With respect to marijuana alone, a study published earlier this year found that cannabis use is associated with significant reductions in dependence on opioids and other prescription drugs, as well as an increase in quality of life
Another study released last year determined that states with active medical marijuana laws saw certain opioid prescription rates drop nearly 20 percent compared to prohibition states.